Current Research of Trichinellosis in China
نویسندگان
چکیده
Trichinellosis, caused by Trichinella, is an emerging or re-emerging zoonotic parasitic disease, which is distributed worldwide with major socio-economic importance in some developing countries. In particular, it has been calculated that more than 40 million people are at risk of Trichinella infection in China. This review summarizes the current information on the epidemiology, laboratory diagnosis and vaccines of trichinellosis in China. Moreover, study of the treatment potential of using Trichinella for immune-related diseases and cancer, as well as the transcription and post-transcription modification of Trichinella were also collected, providing viewpoints for future investigations. Current advances in research will help us to develop new strategies for the prevention and control of trichinellosis and may potentially yield biological agents for treating other diseases.
منابع مشابه
Epidemiology of swine trichinellosis in China.
Swine trichinellosis has been reported in 26 provinces, autonomous regions or municipalities (P/A/M) of China. The prevalence rate in swine varied from 0.12% to 34.2% in five P/A/M, from 0.01% to 0.0001% in other P/A/M. The seroepidemiological survey of swine trichinellosis was carried out by ELISA in seven P/A/M, the seroprevalence varied from 0.09% to 29.63%. The prevalence of Trichinella inf...
متن کاملTrichinella according to their geographical distribution and biological, morphological and biochemical characteristics: Trichinella spiralis; Trichinella nativa; Trichinella britovi; Trichinella pseudospiralis; Trichinella murrelli; Trichinella nelsoni; Trichinella papuae;
The first outbreak of human trichinellosis in China,according to official national publication,was registered in Tibet in 1964. Since then,more than 500 outbreaks, numbering 25 161 cases with 240 deaths, have been recorded.However, this reported quantity is probably highly underestimated because adequate diagnostic techniques might not have been available in the whole area.Moreover, infection i...
متن کاملSerological investigation on human trichinellosis spiralis in Hubei Province of PR China.
PVC-ELISA for detection of human trichinellosis and its value of field application was explored during 1988-1994. Sera of 56 cases of clinically confirmed trichinellosis were tested for serum Trichinella antibodies by way of PVC-ELISA, and the positive rate was 100%. When the sera of 80 cases of healthy persons from non-endemic areas were tested for trichinellosis, they were all negative. For t...
متن کاملA trichinellosis outbreak in Borikhamxay Province, Lao PDR.
Trichinellosis is documented in Southeast Asia, particularly in Thailand and China. Data from Lao PDR are lacking. An outbreak investigation was conducted in Borikhamxay Province after three patients with suspected trichinellosis consulted the Mahosot Hospital, Vientiane. In total, 22 trichinellosis cases were identified; 21 cases could be confirmed by Western blot. High fever (100%), muscle pa...
متن کاملMolecular Identification of a Trichinella Isolate from a Naturally Infected Pig in Tibet, China
The first human case with trichinellosis was reported in 1964 in Tibet, China. However, up to the present, the etiological agent of trichinellosis has been unclear. The aim of this study was to identify a Tibet Trichinella isolate at a species level by PCR-based methods. Multiplex PCR revealed amplicon of the expected size (173 bp) for Trichinella spiralis in assays containing larval DNA from T...
متن کامل